Drug combo aims to stop Post-Birth bleeding, but trial stopped early
NCT ID NCT01113229
First seen Mar 08, 2026 · Last updated Jun 20, 2026 · Updated 15 times
Summary
This study tested whether giving two drugs—oxytocin and misoprostol—together could prevent postpartum hemorrhage (heavy bleeding) after vaginal birth better than oxytocin alone. The trial planned to include over 1,700 women giving birth at 36 to 42 weeks, but it was terminated early, so we don't have full results. The goal was to reduce the number of women losing more than 500 mL of blood within an hour of delivery.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Chi Poissy St Germain
Poissy, 78300, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
oxytocin and misoprostol
What this could lead to
If it worked, this combination could offer a better way to prevent dangerous bleeding after childbirth, saving lives and reducing complications.
What could go wrong
The trial was terminated early, so results are incomplete. The combination may not be more effective than oxytocin alone and could carry added side effects like nausea or fever.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.