Can counseling keep homeless youth off opioids?
NCT ID NCT06311838
First seen Jun 26, 2026 · Last updated Sep 11, 2026 · Updated 2 times
Summary
This study tests two counseling programs—one focused on motivation and coping skills, the other on strengths and advocacy—to prevent opioid misuse in 300 homeless youth aged 14-24. Participants are randomly assigned to one of the programs or standard services, and tracked for two years. The goal is to see which approach best reduces substance use and improves mental health.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Motivational Interviewing/Community Reinforcement Approach (MI/CRA) and Strengths-Based Outreach and Advocacy (SBOA)
- What this could lead to
- If successful, this could provide an effective, scalable program to prevent opioid addiction and improve mental health among homeless youth.
- What could go wrong
- This is an early-stage trial with 300 participants, so results may not apply to all homeless youth. The interventions are behavioral and may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2024
- Expected to finish
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Dec 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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14 to 24 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Youth must meet the criteria for homelessness as defined by the McKinney-Vento Act: children and youth who lack a fixed, regular, and adequate nighttime residence; or live in a welfare hotel, or place without regular sleeping accommodations, or live in a shared residence with other persons due to the loss of one's housing or economic hardship * Must speak english adequately to complete measures Exclusion Criteria: * Youth who have a stable housing situation. * Non-English speaker
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
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Star House
RECRUITINGColumbus, Ohio, 43201, United States
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