Scar prevention showdown: chitosan cream takes on silicone and olive oil
NCT ID NCT07269093
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests three different creams—chitosan, silicone gel, and olive oil—to see which works best at preventing raised scars (hypertrophic scars) after stitches heal. About 120 adults with fresh scars will apply their assigned cream twice daily for 8 weeks. Doctors will check their scars at 4, 12, and 24 weeks using special rating scales.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with traumatic or surgical wounds which have healed by primary intention within 14 days * Length of scar at least 3cm Exclusion Criteria: * Patients with seafood allergy * Patients with scar from wounds that were complicated by infection or wound breakdown * Patients who have undergone scar treatment by other modalities * Patients with history of keloids / hypertrophic scars * Pregnant patients
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital Kuala Lumpur
NOT_YET_RECRUITINGKuala Lumpur, Kuala Lumpur, 50586, Malaysia
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Hospital Pakar Universiti Sains Malaysia
RECRUITINGKubang Kerian, Kelantan, 16150, Malaysia
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Hospital Raja Perempuan Zainab II
NOT_YET_RECRUITINGKota Bharu, Kelantan, 15586, Malaysia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Cold before the needle: new study aims to ease scar treatment pain
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- Laser light may fade scars after major body surgery