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Botox and laser combo tested for burn scars

NCT ID NCT07360483

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether adding botulinum toxin (Botox) to fractional CO2 laser treatment improves raised burn scars more than laser alone. 48 people with hypertrophic burn scars were treated, and scar appearance was measured using standard scales. The goal was to see if Botox, given by injection or through laser-assisted skin delivery, boosts results.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
botulinum toxin type A (Botox)
What this could lead to
If it works, this could point toward a better way to treat raised burn scars with fewer injections.
What could go wrong
This is a small, completed study with only 48 people. Results may not apply to all scar types or skin tones. Botox injections carry risks like bruising or muscle weakness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

48 people

The number who actually took part.

Started

Jan 2025

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Scar Type: Clinically diagnosed hypertrophic burn scar not less than 4.5 cm 2. Minimum Scar Size: 4.5cm x 1 cm 3. Scar duration: At least 1 month old and not exceed 6 months. 4. Fitzpatrick Skin Type: II to IV 5. No Recent Scar Treatment: No scar treatment within the past 6 months 6. Healthy Skin: No active skin infections in the treatment area 7. Normal Neuromuscular Function: No history of neuromuscular disorders or medications affecting muscle function. Exclusion Criteria: * 1\) Pregnancy /Lactation: Pregnant, lactating, or planning pregnancy within 6 months 2) patients did previous intervention for the scar for the last 6 months 3) Bleeding Disorders: Known cases of bleeding disorders 4) patients with allergic reaction to botulinum toxin or with neuromuscular junction diseases (eg, myasthenia gravis) 5) patients on medication that decrease neuromuscular transmission (eg, aminoglycosides, penicillamine, quinine, and calcium channel blockers).

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Conditions

The condition(s) this trial relates to.

Cicatrix, Hypertrophic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypertrophic scars

Contacts and locations

Locations

  • Cairo university

    Cairo, Cairo Governorate, 02002, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.