Micro-Dose sedative calms Post-Surgery agitation
NCT ID NCT07302815
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving a very small dose of a sedative drug (dexmedetomidine) before surgery can prevent the confusion and agitation some patients experience when waking up from anesthesia. The trial involves 120 adults undergoing septoplasty (nose surgery). Half receive the sedative, half receive a placebo, and researchers compare how calm or agitated they are after the procedure.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients of both gender aged 18 to 60 years with American Society of Anesthesiologists (ASA) Physical Status I or II, who were scheduled for septoplasty surgery under general anesthesia. Exclusion Criteria: * Patients declined to participate in the trial. * History or clinical evidence of chronic obstructive pulmonary disease. * History of renal or hepatic dysfunction, sleep apnea syndrome. * Cognitive dysfunction or psychiatric disorder. * Patients receiving beta blocker. * Patients with anticipated difficult airway. * Patients with electro cardiac abnormalities. * Emergency surgeries. * Pregnancy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tanta university
Tanta, Gharbia Governorate, 31527, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Virtual reality could replace sedatives for anxious hip surgery patients
- Can a Mother's lullaby calm children after anesthesia?
- Nose nerve block calms Post-Surgery agitation, study finds
- New study aims to calm kids after surgery with smarter anesthesia