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Simple painkiller may shield seniors from Post-Surgery confusion

NCT ID NCT04093219

First seen Jan 12, 2026 · Last updated Jun 17, 2026 · Updated 24 times

Summary

This study tested whether giving older adults (60+) a common painkiller (IV acetaminophen) every 6 hours during heart surgery recovery could prevent delirium, a state of sudden confusion. The trial involved 900 participants across multiple hospitals. Researchers compared those who received the drug to those who did not, checking daily for signs of delirium until discharge.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Albert Einstein College of Medicine- Montefiore

    The Bronx, New York, 10467, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Columbia University Irving Medical Center

    New York, New York, 10032, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States

  • University of California Irvine

    Irvine, California, 92697, United States

  • University of California Los Angeles

    Los Angeles, California, 90095, United States

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15213, United States

  • Yale University/Yale New Haven Hospital

    New Haven, Connecticut, 06510, United States

Conditions

The condition(s) this trial relates to.

coronary artery disorder delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.