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Brain radiation may stop cancer spread in rare bladder cancer

NCT ID NCT00756639

First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 27 times

Summary

This study tests whether giving whole brain radiation to patients with small cell carcinoma of the urinary tract (including the bladder) can lower their risk of developing brain tumors. The 31 participants have already responded well to chemotherapy. They receive radiation for 3 weeks and are monitored with brain scans for a year to see if the treatment is safe and effective.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiation therapy (whole brain radiation)

What this could lead to

If it works, this could point toward a way to prevent brain metastases in patients with this rare and aggressive bladder cancer.

What could go wrong

This is a small, early-phase trial with only 31 participants, so results may not apply to everyone. Whole brain radiation can cause side effects like memory problems or fatigue.

Conditions

The condition(s) this trial relates to.

adenocarcinoma brain cancer transitional cell carcinoma Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.