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New hope for seniors: preventing Post-Surgery brain fog

NCT ID NCT07576517

First seen May 12, 2026 · Last updated May 23, 2026 · Updated 2 times

Summary

This study tests whether giving older patients (65-90) a combination of two medicines (dexmedetomidine and esketamine) plus a gentle brain stimulation technique (tDCS) around the time of surgery can prevent confusion, memory loss, and other thinking problems that often occur after non-cardiac surgery. About 1,160 participants will be followed to see if these treatments help protect brain function and reduce delirium. The goal is to find a safe way to keep older adults sharp after an operation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • First Affilited Hospital, School of Medicine, Zhejiang University

    Hangzhou, Zhejiang, 310006, China

    Contact Email: •••••@•••••

  • Fujian Medical University Union Hospital

    Fuzhou, Fujian, 362011, China

    Contact Email: •••••@•••••

  • Peking University First Hospital

    Beijing, Beijing Municipality, 100034, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peking University Shenzhen Hospital

    Shenzhen, Guangdong, 518036, China

    Contact Email: •••••@•••••

  • Second Affilited Hospital, School of Medicine, Zhejiang University

    Hangzhou, Zhejiang, 310009, China

    Contact Email: •••••@•••••

  • Xijing Hospital, Air Force Medical University

    Xi'an, Shaanxi, 710032, China

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.