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Brain zaps and puzzles may ward off Alzheimer's in At-Risk seniors

NCT ID NCT02386670

First seen Apr 25, 2026 · Last updated May 22, 2026 · Updated 7 times

Summary

This 7-year study tests whether a combination of gentle brain stimulation (tDCS) and computer-based cognitive exercises can slow mental decline and prevent Alzheimer's dementia. It involves 375 older adults with mild cognitive impairment or depression who are at higher risk. Participants receive either real or placebo treatments to see if the active approach helps preserve memory and thinking skills over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baycrest Centre for Geriatric Care

    Toronto, Ontario, Canada

  • Centre for Addiction and Mental Health

    Toronto, Ontario, Canada

  • St. Michael's Hospital

    Toronto, Ontario, Canada

  • Sunnybrook Heath Sciences Centre

    Toronto, Ontario, Canada

  • University Health Network

    Toronto, Ontario, Canada

Conditions

Explore the condition pages connected to this study.