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One-Hour heart attack test could save lives and slash ER wait times

NCT ID NCT05649384

Diagnosis Sponsor: University Hospital, Basel, Switzerland Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Sep 18, 2026 · Updated 3 times

Summary

This study compares two blood test schedules for diagnosing heart attacks in the emergency room: the standard 3-hour test and a newer 1-hour test. Over 64,000 adults with chest pain will be enrolled to see if the faster test is just as safe and accurate. If it works, patients could get diagnosed and treated much sooner.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
High-sensitivity cardiac troponin blood test
What this could lead to
If successful, this could make heart attack diagnosis faster and safer, reducing ER wait times and improving patient outcomes.
What could go wrong
The trial is observational, not a controlled experiment, so results may not prove cause and effect. The faster test might miss some heart attacks in real-world use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 64,374 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2020

Expected to finish

May 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18 and above * Presentation with acute non-traumatic acute chest pain to the emergency department * Suspicion of acute myocardial infarction Exclusion Criteria: * Terminal kidney failure requiring dialysis * Cardiac arrest * Cardiogenic shock

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Conditions

The condition(s) this trial relates to.

acute myocardial infarction acute subendocardial myocardial infarction Chest Pain Emergencies intermediate coronary syndrome myocardial infarction Non-ST Elevated Myocardial Infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute chest pain Nstemi - non-ST segment elevation mi

Contacts and locations

Locations

  • Attikon General Hospital Athens

    Athens, Greece

  • Azienda Ospedaliera San Giovanni Addolorata

    Roma, Italy

  • Baylor St. Luke's Medical Center

    Houston, Texas, 77030, United States

  • Careggi University Hospital Florence

    Florence, Italy

  • Emergency Institute for Cardiovascular Diseases C.C. Iliescu

    Bucharest, Romania

  • Hospital Città della Salute e della Scienza di Torino

    Torino, Italy

  • Hospital Clinic Barcelona

    Barcelona, Spain

  • Hospital Clínico Universitario Valencia

    Valencia, Spain

  • Kantonsspital Aarau

    Aarau, Switzerland

  • Kantonsspital Luzern

    Lucerne, Switzerland

  • Konkuk University Medical Center

    Seoul, South Korea

  • Royal Cornwall Hospitals Treliske

    Truro, United Kingdom

  • Royal London Hospital

    London, United Kingdom

  • St Andrew's War Memorial Hospital Brisbane

    Brisbane, Australia

  • St. Claraspital

    Basel, Switzerland

  • University Central Hospital Helsinki

    Helsinki, Finland

  • University Hospital October 12 Madrid

    Madrid, Spain

  • University Hospital Ramon y Cajal

    Madrid, Spain

  • University Hospital Zurich

    Zurich, Switzerland

  • Vienna General Hospital (AKH Wien)

    Vienna, Austria

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