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Magnesium before surgery may soothe Kids' Post-Op agitation

NCT ID NCT07082894

Symptom relief Sponsor: Tanta University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving children a single dose of magnesium before tonsil surgery could reduce confusion and agitation when they wake up. 120 children aged 4 to 7 took part. Half received magnesium syrup and half received a placebo (lemon juice). Researchers measured agitation using a standard scale in the recovery room.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
magnesium
What this could lead to
If it works, this could offer a simple, low-cost way to help children wake up calmer after surgery.
What could go wrong
This is a small, single-center study with 120 children. The effect may be modest or not apply to other surgeries or age groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

120 people

The number who actually took part.

Started

Jul 2025

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

4 to 7 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Both gender * 4 to 7 years age * American Society of Anesthesiologists (ASA) Physical Status I or II * Scheduled for adenotonsillectomy surgery under sevoflurane anesthesia Exclusion Criteria: * Parents declined to participate in the trial * Children with behavioral changes; neurological or psychiatric diseases * Physical or developmental delay * Sedative or anticonvulsant medication * Pre-existing renal or cardiovascular disease, bone disease, or gastrointestinal disorders * Allergy to magnesium

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Conditions

The condition(s) this trial relates to.

Emergence Delirium magnesium deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adenotonsillectomy Emergence agitation Magnesium

Contacts and locations

Locations

  • Tanta University

    Tanta, Gharbia Governorate, 31527, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.