Heart-Lung machine at the scene: could it save more cardiac arrest victims?
NCT ID NCT07041086
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether using a heart-lung machine (ECMO) right at the scene of a cardiac arrest can improve survival and brain function. Researchers will compare how quickly ECMO can be started on-site versus in the hospital. The trial involves 100 adults who have a witnessed cardiac arrest and receive bystander CPR.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Extracorporeal membrane oxygenation (ECMO) - a machine that pumps blood outside the body to add oxygen and remove carbon dioxide
- What this could lead to
- If it works, this could show that starting ECMO at the scene of a cardiac arrest saves more lives and reduces brain damage compared to standard CPR alone.
- What could go wrong
- This is a small, early-stage feasibility study, not a large definitive trial. ECMO is complex and risky, and results may not apply to all patients or settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2025
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients after out-of-hospital cardiac arrest
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * Observed collapse and presumption of cardiac cause of cardiac arrest * Estimated age up to 70 years * Baseline rhythm of ventricular fibrillation or pulseless electrical activity (PEA) * Basic bystander cardiopulmonary resuscitation (CPR), "bystander CPR", telephone assisted CPR (TANR) Exclusion Criteria: * Children or adults with estimated weight below 40 kg * Known major comorbidities of the patient suggesting low rehabilitation potential (e.g. chronic obstructive pulmonary disease (COPD) IV, malignancy in tertiary phase)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Emergency Medical Services, Moravian-Silesian Region
RECRUITINGOstrava, Moravian-Silesian Region, 700 30, Czechia
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University Hospital Ostrava
RECRUITINGOstrava, Moravian-Silesian Region, 70852, Czechia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could better phone training save more cardiac arrest victims?
- A needle in the neck to shock the heart back to life?
- Can tracking body heat during cardiac arrest improve survival?
- Can emergency response predict heart restart? a new study investigates
- Can big data unlock the secrets of cardiac arrest survival?