Prepping for knee surgery with exercise may boost results
NCT ID NCT06290336
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether doing supervised exercise and learning about recovery before total knee replacement helps patients feel better and function better one year after surgery. About 110 adults with knee osteoarthritis awaiting surgery will be randomly assigned to either the prehabilitation program or standard care. The main goals are to see if the program improves how aware patients are of their knee and how well they cope after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- pre-operative exercise therapy and education
- What this could lead to
- If it works, this could show that preparing with exercise and education before knee replacement leads to better knee function and satisfaction after surgery.
- What could go wrong
- This is a relatively small trial (110 participants) and the benefits may be modest. The intervention requires time and commitment, and results may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 110 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Waiting list for primary unilateral knee replacement surgery * Osteoarthritis of the knee being the primary reason for surgery * Reside within 60 minutes of travel to the site of the intervention Exclusion Criteria: * Previous knee replacement surgery in the other knee * Other reason than osteoarthritis of the knee as the primary reason for surgery * Impaired cognitive function * Not being independent speaking and reading in swedish language * Chronic illness or disability etc hindering full participation in the intervention
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Linkoping University
RECRUITINGLinköping, Östergötland County, 58183, Sweden
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