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Pre-Surgery workout may boost liver donor recovery

NCT ID NCT05431361

Knowledge-focused Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a personalized exercise program (prehab) before living liver donation is practical and helpful. Thirty donors followed a remote exercise plan for at least 28 days before surgery. The goal was to see if a larger trial is possible, not to prove the program works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Prehabilitation (exercise program)
What this could lead to
If this approach works, it could improve recovery and quality of life for living liver donors after surgery.
What could go wrong
This was a small, early feasibility study with only 30 participants. It was not designed to prove that prehab actually improves recovery, so results may not be conclusive.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Aug 2022

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Fluent in English for the purposes of providing informed consent, completing study-related questionnaires, and understanding intervention and other study requirements * Have a minimum of 28 days prior to scheduled LDLT Exclusion Criteria: * They plan to be absent for more than 2 weeks of the intervention period * Their health status changes during the pre-LDLT procedure which results in the loss of LLD candidacy

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Living donor liver transplantation

Contacts and locations

Locations

  • University Health Network

    Toronto, Ontario, M5G 2C4, Canada

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