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Liver regrowth secrets: new study tracks donor recovery

NCT ID NCT07329296

Knowledge-focused Sponsor: Erasmus Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 90 living liver donors to see how much their liver regrows within a year after donation. Researchers will use CT or MRI scans to measure liver volume and look for factors like age, sex, and weight that might influence regrowth. The goal is to better understand the liver's natural healing process and improve donor care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better predict liver regrowth in living donors, improving donor safety and selection.
What could go wrong
This is an observational study using past and current data, so it cannot prove cause and effect. Results may not apply to all donors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The population consists of adult living liver donors at the Erasmus MC.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: * Living liver donation between May 2004 and June 2026 * Written informed consent In order to be eligible for LDLT, a subject needed to meet all of the following criteria: * 18-60 years old * Physical and mental well-being * Body Mass Index (BMI) \<33 kg/m2 * No active drugs or other substances use Exclusion Criteria: There are no exclusion criteria for this study. Exclusion criteria for LDLT were: Absolute exclusion criteria * Medical conditions (for instance heart disease and bleeding or clotting disorders) * History of liver disease * Previous/active malaria infection * Financial incentive or indications of pressure * Unable to cooperate with designated long-term follow-up * Severe psychiatric disease or psychological instability * Active alcoholism or frequent heavy alcohol use or drugs use/abuse * Unable to give informed consent * History of dementia or other neurological degenerative disorders * Persons with rabies or persons bitten in the past 6 months by an animal and that are treated as if the animal is rabid * Persons with syphilis * Human immunodeficiency virus-positive persons. Relative exclusion criteria * BMI \>33 kg/m2 * Smoking

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Living donor liver transplantation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Erasmus Medical Center

    Rotterdam, South Holland, 3015 GD, Netherlands

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