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Ultrasound-Delivered pain gel shows promise for carpal tunnel sufferers

NCT ID NCT07613476

Symptom relief Sponsor: University of Faisalabad Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a pain-relief gel (pregabalin) delivered through the skin using ultrasound can reduce pain and improve hand function in people with carpal tunnel syndrome. The treatment is given four times a week for a month, and compared to standard ultrasound therapy without the drug. The goal is to find a safer, non-invasive option that avoids the side effects of oral medications.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
pregabalin gel
What this could lead to
If it works, this could offer a non-invasive, low-side-effect treatment option for carpal tunnel pain and hand function.
What could go wrong
This is a small, early-stage trial with only 30 participants, so results may not apply widely. The treatment may not prove better than standard ultrasound therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Jan 2026

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Clinical diagnosis of Carpal Tunnel Syndrome confirmed by positive Phalen's maneuver or Tinel's sign * Age between 20 and 40 years with no painkillers for more than a week * Symptom duration of more than 3 months * Mild to moderate CTS (no thenar muscle atrophy) * Willing to provide written informed consent Exclusion Criteria: * History of steroid injection for CTS in the past 3 months * Prior surgery for Carpal Tunnel Syndrome * Currently pregnant or breastfeeding * Malignancy or any contraindication to ultrasound (e.g., acute infection, bleeding disorder over the wrist) * Presence of cervical radiculopathy * Previous wrist fracture on the affected side * Participation in another interventional trial

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome neuralgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carpal tunnel syndrome (CTS)

Contacts and locations

Locations

  • The University of Faisalabad

    Faisalābad, Punjab Province, 3800, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.