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Can zapping the brain boost coping skills? new study explores

NCT ID NCT07433829

Knowledge-focused Sponsor: The Hong Kong Polytechnic University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed pilot study tested whether a type of brain stimulation called intermittent theta-burst stimulation (iTBS) can temporarily change activity in the prefrontal cortex of 40 healthy adults. Participants received either real or sham stimulation, and researchers measured stress levels and coping strategies. The goal was to understand how brain stimulation might affect coping, which could inform future treatments for depression.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Transcranial Magnetic Stimulation (TMS)
What this could lead to
If successful, this could help researchers understand how brain stimulation changes brain activity and coping skills, potentially guiding future treatments for depression.
What could go wrong
This is a small pilot study in healthy people, not patients. It only measures immediate effects, so results may not apply to real-world mental health conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Jan 2026

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18-60 years old; Exclusion Criteria: * a family history of psychiatric disorders; * history of or currently diagnosed neuropsychiatric conditions; * history of or active systemic illnesses such as cancer, epilepsy, diabetes, hypertension, or other medical conditions; * contraindications to transcranial magnetic stimulation (TMS); * any prior exposure to brain stimulation procedures.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Health adult subjects

Contacts and locations

Locations

  • The Hong Kong Polytechnic University

    Hong Kong, 九龙, China

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