Can a simple ultrasound predict cancer after molar pregnancy?
NCT ID NCT07333326
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will use Doppler ultrasound to measure blood flow in the uterine artery before and after removing a molar pregnancy. The goal is to see if these measurements can predict which patients will develop persistent gestational trophoblastic neoplasia, a type of cancer. Researchers will follow 175 women with complete hydatidiform mole to compare those who recover with those who develop complications.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors identify which patients need closer monitoring after a molar pregnancy, potentially catching complications earlier.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead to a direct benefit for participants, and the results might not change current care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 175 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Female 18:45 years with complete hydatiform mole
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with confirmed diagnosis of complete hydatiform mole. * Hemodynamically stable patient . * No contraindication for anesthetic materials used for the evacuation . * Acceptance of possible prolonged follow up , repeated uterine artery doppler ultrasound ,repeated HCG tests Exclusion Criteria: * Patient refusal to participate in the study. * Patient with incomplete hydatiform mole . * Patients who were lost during the follow-up period after this procedure. * Contraindication for anesthetic materials used for the evacuation .
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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