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New algorithm could help ICU patients get the right rehab at the right time

NCT ID NCT06532994

Knowledge-focused Sponsor: Wuhan University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study aims to create a prediction tool that helps doctors decide which ICU patients who have been on a breathing machine will benefit most from early rehabilitation. Researchers will collect data from 250 patients and use machine learning to build an algorithm. The goal is to improve recovery and reduce complications by targeting rehab to those who need it.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
early rehabilitation intervention (physical and cognitive therapy tailored to patient's consciousness and cooperation level)
What this could lead to
If successful, this could help doctors identify which ICU patients are most likely to benefit from early rehab, leading to better recovery and shorter hospital stays.
What could go wrong
This is an early-stage observational study, not a treatment trial. The algorithm may not work for all patients or in different hospitals, and it won't directly improve health on its own.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 250 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2024

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

ICU patients received mechanical ventilation and early rehabilitation interventions, regardless of the primary diagnosis.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age older than 18 years; 2. Received mechanical ventilation, including endotracheal intubation and tracheostomy, during ICU admission; 3. Met the rehabilitation intervention indications outlined in the "Chinese Expert Consensus on Neurocritical Rehabilitation" during ICU admission and underwent corresponding early rehabilitation interventions, including but not limited to arousal therapy for consciousness disorders, early active/passive mobilization, comprehensive pulmonary rehabilitation, etc.; 4. No mortality events occurred during ICU admission; 5. Informed consent form signed by family members or the patient. Exclusion Criteria: 1. Pediatric patients under 18 years of age; 2. Hospitalized patients in the ICU who did not receive mechanical ventilation; 3. Patients in the ICU who did not undergo early rehabilitation interventions; 4. mortality events occurred during ICU admission; 5. Patients transferred out of the ICU due to treatment abandonment by family members; 6. Family refusal to sign the informed consent form or patient refusal to sign the informed consent form when conscious and competent.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Algorithms Intensive care Mechanical ventilation Rehabilitation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Zhongnan hospital of Wuhan University

    RECRUITING

    Wuhan, Hubei, 430070, China

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