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Eye fluid analysis may predict Post-Surgery dry eye

NCT ID NCT05802550

Knowledge-focused Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study analyzed tear and eye fluid samples from 100 cataract surgery patients to find biomarkers that could predict dry eye disease after surgery. Researchers used advanced chemical analysis to look for clues in the eye's surface cells and inner fluid. The goal is to better understand why some patients develop dry eye and to personalize care in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors predict which patients are at risk for dry eye after cataract surgery, allowing for personalized preventive care.
What could go wrong
This is an observational study, not a treatment trial. It may not find reliable biomarkers, and results may not change clinical practice immediately.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Sep 2023

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * Patient with cortico-nuclear and/or subcapsular cataract * Age \> or = 50 years * Patient affiliated to a social security system * Patient agreeing to participate in the study who provided his/her free and informed written consent Exclusion criteria: * History of ocular surgery or trauma (≤ 3 months) * Other types of cataract excepted age-related or diabetic cataract * Any eye drops or treatments that may interfere with the ocular surface * Lens wearer * Any general pathology with a known impact on the ocular surface (auto-immune disease, allergy) * Proven allergy to povidone-iodine or to a component of the postoperative treatment * Patient under legal protection (safeguard of justice, curatorship and guardianship), or in a situation of deprivation of freedom * Patient unable to understand the nature and objectives of the study

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Conditions

The condition(s) this trial relates to.

cataract senile cataract

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Age-related cataract

Contacts and locations

Locations

  • KHANNA

    Tours, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.