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Can we predict who will have memory issues after brain surgery for Parkinson's?

NCT ID NCT06272968

Knowledge-focused Sponsor: Charite University, Berlin, Germany Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Sep 04, 2026 · Updated 2 times

Summary

This study follows 30 people with Parkinson's disease who are scheduled to receive deep brain stimulation (DBS). Researchers will test whether brain scans, thinking tests, and other measures can predict who might experience cognitive decline after surgery. Participants complete tests before surgery and again at 3, 12, and 60 months after. The goal is to help doctors personalize treatment to avoid cognitive risks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors personalize DBS surgery to reduce the risk of memory or thinking problems after the procedure.
What could go wrong
This is a small, single-center observational study, not a treatment trial. It aims to improve predictions, not to test a new therapy, so direct patient benefits are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2024

Expected to finish

Dec 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

PD patients that are planned to undergo STN-DBS.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of idiopathic Parkinson's Disease * Indication for STN-DBS Exclusion Criteria: * Internistic, surgical or psychiatric contrainidications with respect to the DBS operation or treatment for the STN-DBS group * Dementia * Relevant language barrier

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Emergence Delirium Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive impairment

Contacts and locations

Locations

  • Charité - Universitätsmedizin Berlin

    Berlin, 13351, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.