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AI could spot rare brain complication after carotid surgery

NCT ID NCT05800821

Knowledge-focused Sponsor: State Institution "Republican Scientific and Practical Center" Cardiology, Belarus Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a deep learning model can predict cerebral hyperperfusion syndrome (CHS), a rare but serious brain complication that can occur after carotid artery surgery. Researchers will enroll 500 adults aged 30-80 who are having carotid revascularization. The goal is to identify patients at risk early, so doctors can intervene and prevent severe outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a tool that helps doctors predict and prevent a rare but serious brain complication after carotid artery surgery.
What could go wrong
This is an observational study, not a treatment trial. The deep learning model may not be accurate enough for real-world use, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2023

Expected to finish

May 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who will undergo carotid revascularization procedures

Ages

30 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age between 30 and 80 years. 2. Occlusive-stenotic lesion of the carotid arteries with indications for carotid revascularization. Exclusion Criteria: 1. Systemic vasculitis. 2. Cerebral vessel aneurysms. 3. Arteriovenous malformation of the brain. 4. Primary brain tumor (including metastatic lesions). 5. Epilepsy. 6. History of traumatic brain injury. 7. Demyelinating diseases of the central nervous system. 8. History of neuroinfection. 9. Atrial fibrillation. 10. Frequent supraventricular or ventricular extrasystoles. 11. Chronic heart failure with left ventricular ejection fraction less than 40%. 12. Chronic kidney disease with estimated glomerular filtration rate less than 45 mL/min/1.73 m². 13. Presence of an implanted cardioverter-defibrillator or pacemaker. 14. Presence of contraindications to the medical use of iodine-containing radiographic contrast agents. 15. Patient's unwillingness to continue participating in the study. 16. Absence of a temporal acoustic window for transcranial Doppler ultrasonography.

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Conditions

The condition(s) this trial relates to.

carotid artery disorder carotid stenosis stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carotid artery diseases Carotid artery stenosis Carotid atherosclerosis Cerebral hyperperfusion syndrome

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • State Institution "Republican Scientific and Practical Center "Cardiology"

    RECRUITING

    Minsk, Belarus

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