Tiny study tests whether diet, exercise, and supplements can turn back the clock on aging
NCT ID NCT07523061
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times
Summary
This pilot study is testing whether a 14-day program combining personalized exercise, a Mediterranean diet, and several supplements (vitamin D, omega-3s, multivitamin, and a tomato extract) is feasible for adults aged 55-70 who are at risk for accelerated aging. Only 10 participants will be enrolled, and the main goal is to see if people will stick with the program and complete the assessments. This is not a test of whether the program actually slows aging—just a check to see if a larger, more definitive trial is possible.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- multimodal lifestyle intervention (personalized physical activity, Mediterranean diet, vitamin D, omega-3, multivitamin, Fruitflow)
- What this could lead to
- If successful, this could pave the way for a larger trial testing whether lifestyle changes can slow aging in at-risk adults.
- What could go wrong
- This is a very small pilot (10 people) lasting only 14 days, so it cannot prove any health benefits. It only checks if the program is practical to run.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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55 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Community-dwelling women and men (sex) aged between 55 and 70 years * low daily exercise (i.e. \<4000 steps/day on average in the last month, self-assessment) * low fruit and vegetable intake (\< 3 per day) * at risk for accelerated functional and biological aging based on the following criteria: * overweight (BMI between 25.0 and 29.9) * at least one of the following lab values or at least borderline blood pressure within the mentioned range: * HbA1c 5.7 - 6.4% (pre-diabetes) * LDL 3.4 - 4.1 mmol L-¹ or TG \> 1.7 mmol L-¹ (atherogenesis) * hs-CRP 2 - 3 mg L-¹ (low-grade inflammation) * increase in BP or borderline BP (SBP 130 - 139 / DBP 85 - 89 mmHg) * availability of a smartphone and agrees that it can be used to connect the activity tracker to the internet and consent that data from the activity tracker will be uploaded and analyzed * Ability to communicate, read and write in German * Dietary tolerability of a Mediterranean diet (e.g. vegetables, olive oil, white meat, fish, plant-based proteins) * Ability to swallow supplement capsules Exclusion Criteria: * current smoking or vaping (smoker = More than 100 cigarettes or vapes in a life-time OR quitted less than 15 years ago and smoked more than 8 pack-years OR quitted less than 10 years ago and smoked max. 8 pack-years) * current supplementation with vitamin D and/or omega-3 and/or Fruitflow® and/or Centrum Silver® Adults 50+ multivitamin and/or taking any other multi-vitamin preparate and not willing to forgo during the trial duration * prior (ever used for more than 3 months) or current intake/application of metformin and/or GLP-1 and/or SGLT-2-inhibitor. * Current or recent (previous 12 months) participation in another clinical trial, or plans of such participation during participation in this trial * Presence of the following diagnosed health conditions in the last 4 years: * cancer (except non-melanoma skin cancer) * myocardial infarction, stroke, transient ischemic attack, angina pectoris, or coronary artery intervention * renal impairment and/or liver disease * relevant/severe impairment in mobility that leads to an inability to participate in the exercise component * major visual or hearing impairment * other serious illness that would preclude participation in the intervention components * Living together with another study participant
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Universitäre Altersmedizin Felix Platter
Basel, Canton of Basel-City, 4055, Switzerland
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