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Can Ultrasound-Guided shots use less steroid for knee pain?

NCT ID NCT07544576

Symptom relief Sponsor: Sosi Dzhugarian Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a smaller dose of steroid injected into the knee with ultrasound guidance works as well as a larger dose given without ultrasound. The goal is to reduce side effects while still easing pain. About 140 people with knee osteoarthritis will receive one of the two treatments and report their pain and function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
triamcinolone (corticosteroid) injection
What this could lead to
If successful, this could show that using ultrasound allows a lower steroid dose, reducing side effects while still relieving knee pain.
What could go wrong
This is a small, early-phase study (140 participants) comparing two injection methods, not testing a new drug. Results may not apply to all patients, and the lower dose might prove less effective.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 140 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Subjects who have already been evaluated within at least one of the 4 study clinics with any of the 3 providers who will be administering the treatment * Males or females age 50 and older * Already had completion of imaging of the affected knee(s) via radiography and/or MRI * Imaging demonstrates osteoarthritis of any severity * Diagnosis of primary osteoarthritis of one or both knees * One or more symptoms associated with the osteoarthritis of at least one knee * Patients able to provide informed consent in English and/or Spanish Exclusion Criteria: * Skin infection at or near area of injection site * Recent fracture of the same knee joint within past 6 months * Uncontrolled bleeding disorder * Intra-articular corticosteroid injection within past 3 months * Intra-articular HA injection within the past 3 months * Intra-articular PRP injection within the past 3 months * Presence of prosthetic knee joint in symptomatic knee * Inability to report symptoms due to cognitive impairment * Complete inability to ambulate, even with assistive device * Any person who is pregnant or less than 1 year post-menopause

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee arthritis osteoarthritis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Community Memorial Health Center - North Brent Street, 168 North Brent Street, Suite 302, Orthopedic Surgery Clinic, Ventura, California 93003

    Ventura, California, 93003, United States

  • Community Memorial Health Center - North Brent Street, 168 North Brent Street, Suite 302, Sports Medicine Clinic, Ventura, California 93003

    Ventura, California, 93003, United States

  • Community Memorial Health Center - Pirie Road, 117 Pirie Road, Orthopedic Surgery Clinic, Ojai, California 93023

    Ventura, California, 93003, United States

  • Community Memorial Health Center, 1320 Maricopa Highway, Ojai, California 93023

    Ventura, California, 93003, United States

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