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Pre-Surgery workouts may boost recovery in lung cancer

NCT ID NCT07479407

Symptom relief Sponsor: Hôpital du Valais Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a supervised exercise program, done alongside chemotherapy or immunotherapy, can improve fitness and recovery in patients with locally advanced non-small cell lung cancer. 74 participants will be randomly assigned to either exercise training or usual care. The main goal is to see if exercise boosts peak oxygen uptake before surgery, which is linked to better surgical outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
supervised exercise training
What this could lead to
If it works, this could show that a structured exercise program helps lung cancer patients stay fitter before surgery and recover faster afterward.
What could go wrong
This is a small, early-stage study (74 people) that hasn't started yet. Exercise may not improve fitness enough to change surgical outcomes, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 74 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Apr 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years. * Confirmed diagnosis of stage IIB, IIIA, IIIB or oligo-metastatic stage IV NSCLC. * Planned induction therapy with either chemotherapy, immunotherapy or a combination of immuno-chemotherapy followed by an anatomical pulmonary resection. * Absence of musculoskeletal conditions preventing safe physical exercise. * Absence of any history of uncontrolled or unstable cardiac disease. * Agreement to participate in the study by signing the study specific informed consent form. Exclusion Criteria: * Pregnancy (confirmed by a test if applicable). * Induction therapy already initiated. * Inability to walk independently. * Lack of decision-making capacity. * Oxygen-dependency before the initiation of the induction protocol. * No capacity for discernment. * Does not speak French.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Locally advanced non-small cell lung cancer (NSCLC)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Centre Hospitalier Universitaire Vaudois

    Lausanne, Canton of Vaud, 1005, Switzerland

  • Hôpital de Sion

    Sion, Valais, 1951, Switzerland

  • Hôpitaux Universitaires de Genève

    Geneva, Canton of Geneva, 1205, Switzerland

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