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Could a Parkinson's drug spark joy in depression?

NCT ID NCT04121091

First seen Jan 03, 2026 · Last updated May 23, 2026 · Updated 24 times

Summary

This small pilot study tested whether pramipexole, a drug used for Parkinson's disease, could reduce anhedonia (loss of interest or pleasure) in people with depression. 13 adults with depression and significant anhedonia took the drug alongside their usual antidepressants. Researchers used brain scans and blood tests to understand how the drug works and who might benefit.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Psychiatry Clinic, Lund, Region Skåne

    Lund, 22358, Sweden

Conditions

Explore the condition pages connected to this study.