Supplement combo shows promise for metabolic health in small study
NCT ID NCT06486077
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study tested a dietary supplement program called Power Line in 17 adults with a BMI between 28 and 35. The program includes a meal replacement shake, a green drink, a vascular health product, and a pre-meal fiber supplement. The main goal was to check safety and tolerability, while also looking at effects on blood sugar and cholesterol levels.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Power Line Program (meal replacement shake, green drink, vascular health product, pre-meal fiber supplement)
- What this could lead to
- If it works, this could point toward a dietary supplement approach to help manage markers of metabolic health like blood sugar and cholesterol.
- What could go wrong
- This is a very small, early-stage study with only 17 participants, so results may not apply to everyone. The main goal was safety, not proof of effectiveness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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17 people
The number who actually took part.
- Started
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May 2025
- Finished
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Nov 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 64 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Generally healthy Female, Male and Non-Binary adults, 18-64 years of age (Inclusive) Body Mass Index (BMI): 28.0-34.9 kilograms/meters2 (kg/m2) (Inclusive) Preference given to individuals having a minimum of two of the following markers of metabolic imbalance: fasting blood glucose ≥ 100 milligrams/deciliter (mg/dl), serum triglycerides (TG) \>100 mg/dl, serum high density lipoprotein - cholesterol (HDLc) (male sex \< 40 mg/dl, female sex \< 50 mg/dl), elevated blood pressure (systolic ≥ 120 and /or diastolic ≥ 80), elevated waist circumference (male sex ≥ 40 inches, female sex ≥ 35 inches) Willing to maintain a consistent diet (including medications, vitamins, and supplements) and lifestyle routine throughout the study. Willing to give written informed consent to participate in the Study. Exclusion Criteria: A serious, unstable illness including cardiac, hepatic, renal, gastrointestinal, respiratory, endocrinologic, neurologic, immunologic/rheumatological, or oncological/hematologic disease. Allergies related to ingredients in study products Known infection with HIV, TB or Hepatitis B or C. POCBP: Not using effective contraception. Blood Pressure medications or supplements Diabetes medications or supplements Cholesterol/Triglyceride lowering medications or supplements Currently taking nutritional supplements judged by the study coordinator to negate or camouflage the effects of the study products Use of Narcotics during the last 30 days Use of Anticoagulants during last 30 days Use of Corticosteroids during the last 30 days Use of controlled substances on a recreational basis during the last 30 days. Consumption of more than 3 alcoholic beverages per day. One beverage is a 5-ounce glass of wine, 12 ounces of beer, or one ounce of hard liquor. Inability to comply with Study and/or follow-up visits. Any concurrent condition (including clinically significant abnormalities in medical history, physical examination, or laboratory evaluations) which, in the opinion of the PI, would preclude safe participation in this study or interfere with compliance. Any sound medical, psychiatric, and/or social reason which, in the opinion of the PI, would preclude safe participation in this Study or interfere with compliance. \-
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Hughes Center for Research and Innovation
Lehi, Utah, 84043, United States
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