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POWER II trial: could Pre-Surgery hormone pills spare older women from radiation?

NCT ID NCT06507618

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 28 times

Summary

This study is for women aged 65 and older with early-stage, hormone-sensitive breast cancer. It tests whether taking hormone therapy for 3 months before surgery helps patients and doctors make better decisions about whether radiation is needed afterward. Half the participants will receive this pre-surgery hormone therapy, while the other half will proceed directly to standard surgery. The goal is to see if this approach reduces unnecessary radiation and improves treatment choices.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • INOVA Schar Cancer

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact Phone: •••-•••-••••

  • University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22903, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Virginia Community Health

    RECRUITING

    Culpeper, Virginia, 22701, United States

    Contact Email: •••••@•••••

  • Virginia Commonwealth University

    RECRUITING

    Richmond, Virginia, 23298, United States

    Contact Email: •••••@•••••

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06511, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.