Can exercise during weight loss keep Teens' metabolism firing?
NCT ID NCT04902001
First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time
Summary
This study looks at how a 12-week weight loss program—combining nutrition advice, exercise, and psychological support—changes the way teenagers with obesity burn energy. Researchers want to understand the separate roles of metabolic and mechanical load on energy expenditure during walking. The goal is to find ways to prevent the weight regain that often happens after weight loss.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Multidisciplinary weight loss program combining nutritional education, physical activity, and psychological support
- What this could lead to
- If successful, this could help design more effective weight loss programs for adolescents that reduce the likelihood of weight regain.
- What could go wrong
- This is a small, early-stage study (21 participants) that focuses on understanding mechanisms rather than proving a treatment works. Results may not apply to all adolescents with obesity.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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21 people
The number who actually took part.
- Started
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Aug 2021
- Finished
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Apr 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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12 to 16 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * being aged 12-16 years old * no contraindication to physical exercise * no cardiovascular disease * BMI above the 97th percentile * candidate to a weight loss intervention Exclusion Criteria: * surgery and medical conditions preventing them to perform the intervention * Weight loss during the previous 6 months * medication that could interfere with energy metabolism. * pregnancy * regular tobacco and alcool use
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU clermont-ferrand
Clermont-Ferrand, France
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Other studies related to the condition(s) this trial covers.
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