New study aims to stop diabetes before it starts in moms with gestational diabetes
NCT ID NCT07269405
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a 3-year program of diet advice, exercise coaching, and behavior support can prevent type 2 diabetes in 800 women who had gestational diabetes. Participants will receive personalized meal plans and regular sessions with dietitians and exercise instructors. The goal is to see if this approach reduces blood sugar problems and improves long-term health for both mothers and their children.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 800 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Mar 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Women with a history of gestational diabetes mellitus and one additional risk factor (obesity, family history of diabetes, impaired fasting glycemia and/or impaired glucose tolerance and/ and or risk understanding by yourself RUBY score of ≥ 8) at 6-12 weeks postpartum 2. Singleton pregnancy 3. Willingness, ability and commitment to comply with study procedures 4. In the opinion of the investigator, absence of any physical limitations, addictive diseases, or underlying medical conditions (including mental health) that may preclude the patient from being a suitable study candidate. 5. Normally residing in Hong Kong 6. Able to communicate in Chinese 7. Written informed consent to participate in the study provided by the patient Exclusion Criteria: 1. Known current diabetes 2. Current or previous use of glucose-lowering or weight loss drugs at screening 3. Concurrent participation in other weight loss or lifestyle intervention programmes 4. Any active acute or chronic disease or condition that, in the opinion of the investigator, might interfere with the performance of this study 5. Any active acute or chronic infectious disease that, in the opinion of the investigator, would pose an excessive risk to study staff 6. Current use or recent exposure to any medication that in the opinion of the investigator could have an influence on the patient's ability to participate in this study or on the performance of the test device 7. Known uncontrolled thyrotoxicosis 8. Current use of steroids 9. Known current or recent alcohol or drug abuse 10. Currently participating in another investigational study protocol where the testing or results may interfere with study compliance, diagnostic results, or data collection 11. An identified protected vulnerable patient (including but not limited to those in detention, or a prisoner)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of Medicine and Therapeutics, The Chinese University of Hong Kong (CUHK), Ward 3M, Diabetes and Endocrine Research Centre, 3/F Day Treatment Block and Children Wards (Old Block), Prince of Wales Hospital
Shatin, Hong Kong
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Family support may curb obesity risk in children of mothers with gestational diabetes
- Can a blood test or eye scan predict pregnancy risks?
- Morning or evening walk? study finds best time to exercise for gestational diabetes
- New study aims to uncover hidden challenges of pregnancy in somaliland