Nerve block may cut opioid use after nose job
NCT ID NCT05667324
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a nerve block (injection of numbing medicine) could reduce pain and the need for strong painkillers after septorhinoplasty, a surgery to fix a deviated nasal septum. Fifty adults received either the nerve block or a placebo. Researchers measured pain scores and recovery time. The goal is to find a safer way to manage post-surgery pain.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Ropivacaine and Dexamethasone injection
- What this could lead to
- If effective, this nerve block could offer a way to manage pain after nose surgery with fewer opioids.
- What could go wrong
- This is a small, completed Phase 4 trial with only 50 participants. The results may not apply to all patients or surgeries.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
-
50 people
The number who actually took part.
- Started
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Apr 2023
- Finished
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Feb 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient presenting for open or endoscopic septorhinoplasty * Age 18-80 * Normal oral food and water intake before surgery * ASA physical classification 1-3 Exclusion Criteria: * Refusal to consent * Patients without a cellular phone or who are unable to accept text messages * Allergy to opioid narcotics * ASA physical classification of 4 or higher * Patient requires other surgery in addition to septorhinoplasty * Age \> 80 or \<18 * Any underlying chronic pain condition or ongoing opioid use over the preceding 3 months * Presence of any other factor which, at the discretion of any member of the study team, makes the patient a poor candidate for block placement. * Presence of any other factor which, at the discretion of any member of the study team, makes the patient a poor candidate for research participation. * Pregnant women
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UF Health of University of Florida
Gainesville, Florida, 32610, United States
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