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Could a portable MRI replace bulky scanners for brain checks?
NCT ID NCT04436068
First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 2 times
Summary
This study tests a small, portable MRI machine for scanning the brains of 100 adults with hydrocephalus or other neurological conditions. Participants get both the portable scan and a standard CT or MRI on the same day. The goal is to see if the portable device can reliably detect fluid buildup and other brain issues, making imaging easier and more accessible.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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100 people
The number who actually took part.
- Started
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Jun 2019
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older * Suspected or confirmed diagnosis of hydrocephalus from Penn referring physician * Other suspected or confirmed neurological disorder from Penn referring physician * Routine clinical CT or MRI of the brain scheduled/obtained on the same day as Hyperfine imaging. * Informed consent obtained from patient or legally authorized representative Exclusion Criteria: * Contraindications to routine 1.5T MRI evaluation, including electrical implants such as cardiac pacemakers or perfusion pumps, ferromagnetic implants such as aneurysm clips, surgical clips, protheses, artificial hearts or heart valves with steel parts, metal fragments, shrapnel, tattoos near the eye, steel implants, or other irremovable ferromagnetic objects * History of uncontrolled seizures * Claustrophobia * Weight greater than or equal to 400lbs (181.4kg) * Pregnancy * Inability or suspected inability to comply with the study procedures
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Other studies related to the condition(s) this trial covers.
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