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Red wine without the alcohol: a new weapon against aging?

NCT ID NCT06871384

Disease control Sponsor: University Rovira i Virgili Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether drinking non-alcoholic red wine, which is rich in natural compounds called polyphenols, can help older adults keep their thinking sharp and muscles strong. Researchers will give 72 people aged 60-74 either non-alcoholic red wine or water, both as part of a Mediterranean diet, and track changes in memory, grip strength, and gut health over time.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
non-alcoholic red wine (rich in polyphenols)
What this could lead to
If it works, this could point toward a simple dietary addition that helps older adults maintain memory and muscle strength as they age.
What could go wrong
This is a small, early-stage study with only 72 participants, so results may not apply to everyone. The effects may be modest or not significant.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 72 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2025

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 74 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1\. Men or women between 60-74 years old; Sensory tolerance to red wine; Written informed consent provided before the initial screening visit. Exclusion Criteria: 1. Men or women \>75 years old, 2. Hypoglucaemiant treatment or type 1 and type 2 diabetes mellitus diagnosed 3. Anaemia (hemoglobin ≤13 g/dL in men and ≤12 g/dL in women) 4. Subjects diagnosed of intestinal disorders such as chron disease, colitis ulcerous, and irritable bowel syndrome 5. To present a clinical active chronic disease 6. To present severe sarcopenia 7. To present cognitive impairment (MMSE ≤ 24 or clinical diagnosis of mild cognitive impairment or dementia) 8. Dietary allergies to: Mediterranean foods (eg, nuts), sulphytes or nitrates 9. Use of antioxidants supplements 10. Regular consumers of red wine who do not agree to change the consumption of red wine with alcohol to nonalcholized wine during the intervention 11. Chronic alcoholism 12. Current or past participation in a clinical trial or consumption of a research product in the 30 days prior to inclusion in the study 13. Failure to follow the study guidelines. For participation in the muscle biopsy, additional exclusion criteria included: Use of prescription anti-platelet medication; Prescription anticoagulant use (or antiaggregant, or acenocoumarol; Conditions which would reduce healing; or known allergy to lidocaine.

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Conditions

The condition(s) this trial relates to.

atrophic muscular disease cognitive disorder Cognitive Dysfunction Muscular Disorders, Atrophic Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive disorders Muscular disorders, atrophic

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Instituto de Ciencias de la Vid y del Vino-ICVV (Consejo Superior de Investigaciones Científicas-CSIC, Universidad de La Rioja, Gobierno de La Rioja)

    ACTIVE_NOT_RECRUITING

    Logroño, Spain, Spain

  • Lyfestyle, Microbiota and Health Unit, Health Sciences Faculty, University of La Rioja

    ACTIVE_NOT_RECRUITING

    Logroño, Spain, Spain

  • Universitat Rovira i Virgili, Facultat de Medicina i Ciències de la Salut, Functional Nutrition, Oxidation, and Cardiovascular Diseases Group (NFOC-Salut)

    RECRUITING

    Reus, Spain, 43201, Spain

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