Weekly exercise may lift mood in Alzheimer's patients
NCT ID NCT03866018
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether a weekly hour of adapted physical activity for 12 weeks could improve self-esteem and motivation in 17 older adults with mild to major cognitive disorders like Alzheimer's. Researchers measured changes in self-esteem, motivation, and apathy. The goal is to see if exercise can be a helpful non-drug approach to improve emotional well-being in this group.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- adapted physical activity
- What this could lead to
- If it works, this could offer a simple, non-drug way to boost mood and motivation in people with cognitive decline.
- What could go wrong
- This was a very small study (17 people) with no control group, so results may not be reliable or apply to everyone. The effect on thinking or memory was not measured.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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17 people
The number who actually took part.
- Started
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Mar 2019
- Finished
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Jul 2020
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or Female ≥ 60 years old * MMSE score between 4 and 26 / 30 * Diagnosis of minor to major NeuroCognitive Disorder of the Alzheimer type or multiple etiology; * Subject without a major hearing or visual impairment; * Subject not presenting any contraindications to the practice of adapted physical activity; * Subject affiliated to Social Security System; * Signing informed consent Exclusion Criteria: * \< 60 years * Medical indications: Recent or unstable cardiovascular events: ECG changes, unstable angina, uncontrolled arrhythmia, 3rd degree BAV, acute heart failure. * MMSE score \< 4 * Subject already engaged in appropriate physical activity * Subject with a perceptual disorder (AMD, deafness...) * Subject with a motor disability * Subject under guardianship, curatorship or safeguard of justice * Persons deprived of their liberty (administrative or judicial)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Institut Claude Pompidou - Centre Mémoire de Ressources et de Recherche du CHU de Nice
Nice, 06100, France
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