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Berry compounds may tame gut inflammation, study suggests

NCT ID NCT04100200

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how natural compounds in strawberries and raspberries (polyphenols) affect inflammation and gut bacteria in overweight adults with mild inflammation. About 105 participants will eat berry products or a control diet for 4 weeks. Researchers will measure blood and stool markers to understand the link between diet, gut microbes, and inflammation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

105 people

The number who actually took part.

Started

Oct 2019

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * C-Reactive Protein (hs-CRP) \> 1.0 and ≤ 10 ng/L * BMI ≥ 25 kg/m2 * Aged 20-60 years * Able to provide informed consent and comply with study procedures * Willing to maintain stable body weight and follow his/her habitual diet and physical activity patterns throughout the trial. * Judged by the Investigator to be in general good health on the basis of medical history and screening laboratory tests. * People with no documented disease condition that would interfere with the study endpoints (ie., CVD, diabetes, hypertension, major organ diseases) or taking medication or dietary supplements that may interfere with study endpoints Exclusion Criteria * Current smoker or marijuana user * No history or presence of atherosclerosis/cardiovascular disease, inflammatory disease, diabetes mellitus, or other systemic diseases, psychological or psychiatric disorders that may interfere with study outcomes. * Taking any medications and/or supplements that would interfere with outcomes of the study (i.e., lipid-lowering medications, anti-inflammatory drugs, etc) * Take part in prebiotics, probiotics or drugs active on gastrointestinal motility or a laxative of any class within 1 month * Unstable use of any medication/supplement, this could include marijuana used as -needed for medical reasons * Have a history of cancer, except for non-melanoma skin cancer in past 5 years * Addicted to drugs and/or alcohol (\>4 drinks/day) * Have been exposed to any non-registered drug product within last 30 days. * Working overnight (e.g. 3rd shift of overnight workers) * Excessive exercisers or trained athletes * Have allergies/intolerances to any of the study products. * Extreme dietary habits (ie. vegetarian/vegan) * Excessive coffee/tea drinker (\>4 cups/day) * Actively losing weight/ trying to lose weight (unstable body weight fluctuations of \> 5 kg in 3 months) * Donated blood within last 3 months * Participated in a clinical trial within 1 month * Female who is pregnant, planning to be pregnant, breastfeeding * Any condition the Investigator believes would interfere with his or her ability to provide informed consent or comply with the study protocol, or which might confound

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinical Nutrition Research Center

    Chicago, Illinois, 60616, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.