Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could a zinc supplement soothe baby reflux?

NCT ID NCT06678997

Symptom relief Sponsor: University of Roma La Sapienza Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether Polaprezinc (Zinc-L carnosine) can reduce reflux symptoms in infants aged 1-12 months. Sixty babies were given either the supplement or a thickened formula twice daily for 8 weeks. Researchers measured changes in a reflux symptom questionnaire to see if the supplement helped.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Polaprezinc (Zinc-L carnosine)
What this could lead to
If it works, this could offer a new, drug-free option to ease reflux symptoms in infants.
What could go wrong
This is a small, early-stage trial with only 60 infants. The results may not apply to all babies, and the supplement might not work better than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Dec 2024

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

1 month to 12 months

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with infant regurgitation accoding to Rome IV criteria * Healthy infants aged 1-12 months * I-GERQ-R score ≥ 16 at baseline Exclusion Criteria: * Organic disease * Current or pregress use of pharmacological treatment for gastric acid suppression or current use of thickened formula * Past history of preterm birth or atopy * Absence of informed consent

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Gastroesophageal reflux (GER) are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

gastroesophageal reflux disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gastroesophageal reflux (GER) Infants

Contacts and locations

Locations

  • UOC Pediatria - Azienda Ospedaliero-Universitaria Sant'Andrea

    Rome, Italy, 00189, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.