Could a zinc supplement soothe baby reflux?

NCT ID NCT06678997

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether Polaprezinc (Zinc-L carnosine) can reduce reflux symptoms in infants aged 1-12 months. Sixty babies were given either the supplement or a thickened formula twice daily for 8 weeks. Researchers measured changes in a reflux symptom questionnaire to see if the supplement helped.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Polaprezinc (Zinc-L carnosine)

What this could lead to

If it works, this could offer a new, drug-free option to ease reflux symptoms in infants.

What could go wrong

This is a small, early-stage trial with only 60 infants. The results may not apply to all babies, and the supplement might not work better than standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastroesophageal reflux disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UOC Pediatria - Azienda Ospedaliero-Universitaria Sant'Andrea

    Rome, Italy, 00189, Italy