Pill power: oral antibiotics may replace IV for infected broken bones
NCT ID NCT05699174
First seen Feb 02, 2026 · Last updated May 24, 2026 · Updated 10 times
Summary
This study tests whether taking antibiotics by mouth for 6 weeks works as well as getting them through an IV for people with infected broken bones that didn't heal properly. About 250 adults will be randomly assigned to one of the two treatments, along with surgery. The goal is to see if oral antibiotics can reduce hospital stays, complications, and costs while still controlling the infection.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Atrium Health, Carolinas Medical Center
NOT_YET_RECRUITINGCharlotte, North Carolina, 28207, United States
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Hennepin Health
RECRUITINGMinneapolis, Minnesota, 55487, United States
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Indiana University
RECRUITINGIndianapolis, Indiana, 46202, United States
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Jamaica Hospital Medical Center
NOT_YET_RECRUITINGQueens, New York, 11418, United States
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Penn State University M.S. Hershey Medical Center
RECRUITINGHershey, Pennsylvania, 17033, United States
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Sinai Hospital Baltimore
NOT_YET_RECRUITINGBaltimore, Maryland, 21215, United States
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University of Maryland , MD Department of Orthopaedics
RECRUITINGBaltimore, Maryland, 21201, United States
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University of Okalahoma College of Medicine
NOT_YET_RECRUITINGOklahoma City, Oklahoma, 73104, United States
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University of Texas Health Science Center at Houston
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
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University of Washington Harborview Medical Center
RECRUITINGSeattle, Washington, 98195, United States
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University of Wisconsin
RECRUITINGMadison, Wisconsin, 53705, United States
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Vanderbilt Medical Center
RECRUITINGNashville, Tennessee, 37203, United States
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Wake Forest University Baptist Medical Center
RECRUITINGWinston-Salem, North Carolina, 27106, United States
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