New pill targets hard-to-treat cancers with specific gene flaw
NCT ID NCT07284186
First seen Dec 17, 2025 · Last updated Jun 22, 2026 · Updated 26 times
Summary
This study tests a new experimental drug called PLX-61639 for people with advanced solid tumors that have a specific genetic change (SMARCA4 mutation) and have stopped responding to standard treatments. The drug is taken as a daily pill and aims to shrink or control the cancer. About 155 adults will take part to see if the drug is safe and how well it works.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Research Site
RECRUITINGScottsdale, Arizona, 85258, United States
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Research Site
RECRUITINGDuarte, California, 91010, United States
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Research Site
RECRUITINGOrange, California, 92868, United States
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Research Site
RECRUITINGBoston, Massachusetts, 02114, United States
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Research Site
RECRUITINGSt Louis, Missouri, 63110, United States
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Research Site
RECRUITINGNew York, New York, 10044, United States
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Research Site
RECRUITINGDurham, North Carolina, 27710, United States
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Research Site
RECRUITINGCleveland, Ohio, 44106, United States
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Research Site
RECRUITINGSan Antonio, Texas, 78229, United States
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Research Site
RECRUITINGFairfax, Virginia, 22031, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.