New pill targets hard-to-treat cancers with specific gene flaw

NCT ID NCT07284186

First seen Dec 17, 2025 · Last updated Jun 07, 2026 · Updated 25 times

Summary

This study tests a new experimental drug called PLX-61639 for people with advanced solid tumors that have a specific genetic change (SMARCA4 mutation) and have stopped responding to standard treatments. The drug is taken as a daily pill and aims to shrink or control the cancer. About 155 adults will take part to see if the drug is safe and how well it works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    Scottsdale, Arizona, 85258, United States

  • Research Site

    RECRUITING

    Duarte, California, 91010, United States

  • Research Site

    RECRUITING

    Orange, California, 92868, United States

  • Research Site

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02114, United States

  • Research Site

    RECRUITING

    St Louis, Missouri, 63110, United States

  • Research Site

    RECRUITING

    New York, New York, 10044, United States

  • Research Site

    RECRUITING

    Durham, North Carolina, 27710, United States

  • Research Site

    RECRUITING

    Cleveland, Ohio, 44106, United States

  • Research Site

    RECRUITING

    San Antonio, Texas, 78229, United States

  • Research Site

    RECRUITING

    Fairfax, Virginia, 22031, United States

Conditions

Explore the condition pages connected to this study.