HIV cure hope: three old drugs aim to flush out and destroy hidden virus
NCT ID NCT07384624
First seen Feb 03, 2026
Summary
This early-stage trial tests whether a combination of three existing drugs (topiramate, lenalidomide, and pyrimethamine) can wake up dormant HIV hiding in the body and then help the immune system eliminate those infected cells. The goal is a 'functional cure' where the virus is controlled without lifelong medication, but participants will remain on antiretroviral therapy during the study. 30 adults with well-controlled HIV will participate across four medical centers in the Netherlands.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HIV (HUMAN IMMUNODEFICIENCY VIRUS) are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Email: •••••@•••••
Locations
-
Amsterdam University Medical Center
Amsterdam, Netherlands
Contact
Contact
Contact
-
Erasmus MC
Rotterdam, Netherlands
Contact
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Email: •••••@•••••
Contact
Contact
Contact
Contact
Contact
Contact
Contact
Contact
Contact
Contact
-
Radboud University Medical Center
Nijmegen, Netherlands
Contact
Contact
Contact
-
University Medical Center Utrecht
Utrecht, Netherlands
Contact Email: •••••@•••••
Contact
Contact
Contact
Contact
Contact
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.