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Blood products may ease wisdom tooth recovery

NCT ID NCT07320170

Symptom relief Sponsor: Recep Tayyip Erdogan University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether two substances made from a patient's own blood—platelet-rich plasma (PRP) and concentrated growth factor (CGF)—can reduce pain, swelling, and dry socket after wisdom tooth removal. 42 healthy adults with impacted wisdom teeth took part. Results will show if these natural treatments improve healing compared to standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

42 people

The number who actually took part.

Started

May 2024

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged between 18 and 50 years. * Systemically healthy individuals classified as American Society of Anesthesiologists (ASA) Class I or Class II. * Presence of impacted mandibular third molars (teeth 38 and 48 according to Fédération Dentaire Internationale (FDI) notation). * Mesioangular impaction with bone retention according to Winter's classification. * Class II relationship to the ramus according to the Pell and Gregory classification. * Level B or Level C depth of impaction according to the Pell and Gregory classification. Exclusion Criteria: * Patients younger than 18 years. * Habitual smoking or alcohol consumption. * Presence of coagulation (bleeding) disorders. * Systemic diseases affecting wound healing or use of medications that compromise healing. * Pregnancy or lactation. * Presence of active pericoronitis associated with the tooth. * Presence of pathological lesions (cysts or tumors) associated with the impacted tooth. * Uncontrolled periodontal disease in the oral cavity. * Known allergy to any medications used in the study protocol. * Inability to comply with follow-up visits.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Impacted third molar

Contacts and locations

Locations

  • Recep Tayyip Erdogan University, Faculty of Dentistry

    Rize, Turkey (Türkiye)

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