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Your own blood may speed wisdom tooth recovery

NCT ID NCT06244797

Symptom relief Sponsor: esengul sen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a special blood product called platelet-rich fibrin (PRF), made from a patient's own blood, can reduce pain, swelling, and jaw stiffness after impacted wisdom tooth extraction. 75 healthy adults aged 18-40 took part. The PRF was placed into the tooth socket after removal, and recovery was tracked for a week. The goal was to see if this simple, natural approach could make the days after surgery more comfortable.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Platelet-rich fibrin (PRF) made from the patient's own blood
What this could lead to
If it works, this could give dentists a simple, natural way to help people recover faster and with less discomfort after wisdom tooth extraction.
What could go wrong
This is a small, single-center study with 75 healthy young adults, so results may not apply to everyone. The improvement may be small and not noticeable in daily life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

75 people

The number who actually took part.

Started

Dec 2023

Finished

May 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Volunteer ASA I individuals between the ages of 18-40 Exclusion Criteria: * Those who are pregnant or lactating * Those receiving anticoagulant or antiplatelet drug therapy * Those who received radiotherapy to the head and face area * Those who are allergic to local anesthetics and prescribed medications

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Impacted third molar tooth

Contacts and locations

Locations

  • Tokat Gaziosmanpaşa Üniversitesi

    Tokat Province, Kaleardı Neighbourhood, Turkey (Türkiye)

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