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Plasma swap shows promise for deadly sepsis in early trial

NCT ID NCT04057872

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 27 times

Summary

This early-stage study tested whether a procedure called therapeutic plasma exchange (TPE) is safe for adults with septic shock, a life-threatening infection that causes organ failure. Seventeen patients received TPE within 24 hours of diagnosis, where their blood plasma was removed and replaced with fluids or blood products. The main goal was to check for side effects and see if patients could complete the treatment, not to prove it works as a cure.

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Contacts and locations

Locations

  • Peter Lougheed Centre

    Calgary, Alberta, T3M 1M4, Canada

  • South Health Campus

    Calgary, Alberta, T3M 1M4, Canada

Conditions

Explore the condition pages connected to this study.