Could Plant-Based hospital drinks be as good as Milk-Based ones? a new study aims to find out
NCT ID NCT07399886
First seen Jun 26, 2026 · Last updated Aug 12, 2026 · Updated 3 times
Summary
This pilot study tests whether it's possible to run a larger trial comparing plant-based and animal-based oral nutritional supplements (ONS) in hospital patients at risk of malnutrition. Sixty patients from two Dutch hospitals will be randomly assigned to receive either a soy-based or milk-based drink for three months. The main goal is to see if patients will stick with the drinks and if the study measurements are practical, not to prove which drink is better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- oral nutritional supplements (plant-based vs animal-based)
- What this could lead to
- If successful, this study could show that a larger trial comparing plant-based and animal-based nutritional drinks is possible, potentially leading to more sustainable hospital nutrition options.
- What could go wrong
- This is a small pilot study with only 60 participants, focused on feasibility rather than health outcomes. It may not show clear differences between the two types of supplements.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2025
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Clinical patients with cancer and lung diseases, cardiology patients, patients with cardiothoracic surgery, and orthopaedic patients age ≥18 years, and treated at Radboudumc or Maastricht UMC+. * Patients who have been advised at least 2 bottles of ONS daily based on a high risk of malnutrition (MUST≥2, PG-SGA-SF≥ 9) and/or by the dietitians expertise. * Written informed consent (IC) Exclusion Criteria: * Patients who are or become dependent on tube or parenteral nutrition * Patients where life-extending therapy is no longer possible * Unable to follow up study instructions * Lactose intolerance * Soy allergy/intolerance * Vegan diet
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Maastricht University Medical Center
RECRUITINGMaastricht, Limburg, 6229 HX, Netherlands
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Radboud university medical center
RECRUITINGNijmegen, Gelderland, 6525 GA, Netherlands
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Other studies related to the condition(s) this trial covers.
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- Searching for biomarkers to combat malnutrition
- One diet plan to fight two forms of malnutrition in kids?