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Scientists investigate cell 'Cleanup' in troubled pregnancies

NCT ID NCT06779916

Knowledge-focused Sponsor: Centre Hospitalier Universitaire de Nīmes Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study examines how cells in the placenta manage waste and self-destruction in women with pregnancy complications like pre-eclampsia and intrauterine growth restriction. Researchers will take blood and urine samples from 50 pregnant women throughout their pregnancy and at delivery. The goal is to understand the underlying cell problems and find new markers to screen for these serious conditions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could point toward new ways to screen for and manage pregnancy complications like pre-eclampsia and growth restriction.
What could go wrong
This is a small, early observational study, not a treatment trial. It may not lead to any practical screening tools or changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

May 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

An initial analysis of the data will make it possible to describe the population. Quantitative variables will be expressed as mean and standard deviation, or median and quartiles. Qualitative variables will be expressed in headcount and percentage.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Pregnant women developing a placental vascular complication (preeclampsia and/or intrauterine growth retardation), hospitalized and delivering at Nimes University Hospital. * Pregnant woman with free and informed consent. * Pregnant woman affiliated with and/or benefiting from a health insurance scheme. Exclusion criteria: * Multiple pregnancy. * Presence of hypertension and/or proteinuria prior to pregnancy. * Participant in an interventional drug study. * Persons in a period of exclusion determined by another study. * Persons under court protection, guardianship or curatorship. * Persons unable to give consent. * Persons for whom it is impossible to give informed information.

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Conditions

The condition(s) this trial relates to.

fetal growth restriction preeclampsia pregnancy disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Growth retardation, intrauterine Pre-eclampsia Pregnancy complications

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Nimes University Hospital

    RECRUITING

    Nîmes, France

More trials for these conditions

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