Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Are hidden immune defects causing your recurring infections? new study investigates.

NCT ID NCT02972281

Knowledge-focused Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked for hidden immune system problems in adults who get frequent or severe bacterial infections, like pneumonia or meningitis. Researchers screened 120 adults aged 18-65 to see how many had an undiagnosed primary immunodeficiency. The goal was to find out if these conditions are being missed in adults with no other known cause for their infections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

120 people

The number who actually took part.

Start date

Mar 2015

Finished

Mar 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18-65 yrs old patients * ≥ 2 bacterial upper or lower respiratory tract infections/years, for at least 2 years, or * ≥ 1 severe bacterial upper or lower respiratory tract infection requiring hospitalization and IV antibiotics, or * ≥ 1 invasive infection (meningitis, bacteriemia, arthritis) due to Streptococcus pneumoniae, group A Streptococcus, Haemophilus influenzae, Neisseria meningitidis or Neisseria gonorrhoeae Exclusion Criteria: * concomitant, systemic comorbidity that predisposes to infection (solid or hematological cancer, diabetes mellitus, severe alcohol or intravenous drug abuse, chronic liver or kidney failure, human immunodeficiency virus infection, anatomic or functional asplenia, drug-induced 1 neutropenia, or solid organ or hematopoietic stem cell transplantation). * the presence of a local predisposing factor: cigarette smoking (\> 5 pack-year and/or 5 cigarettes/day), underlying infection (tuberculosis, influenza…), chronic obstructive pulmonary disease, cystic fibrosis or bronchiectasis for pulmonary infections; cerebrospinal leak or preceding upper respiratory tract (URT) infections for non-meningococcal meningitis; oral, dental or skin condition for GAS infections * use of corticosteroids, non-steroidal anti-inflammatory drugs, immunosuppressants or cytotoxic chemotherapeutics * PID diagnosed before the infectious episode in question. * current or recent pregnancy * hospital-acquired infection (including infections of prostheses).

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Antibody deficiency are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

agammaglobulinemia bacterial meningitis bacterial pneumonia chronic rhinosinusitis complement deficiency haemophilus infectious disease Hereditary Complement Deficiency Diseases inborn error of immunity otitis media pneumococcal infection streptococcal infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Antibody deficiency Chronic sinus infection Complement deficiency Haemophilus influenza Meningitis, bacterial Neisseria infections Otitis media Pneumococcal infections Pneumonia - bacterial Streptococcal infection

Contacts and locations

Locations

  • C.H de Roubaix

    Roubaix, France

  • CH ARRAS

    Arras, France

  • CH DOUAI

    Douai, France

  • CH LENS

    Lens, France

  • CHRU,

    Lille, France

  • Ch Armentieres

    Armentières, France

  • Ch Arrondissement de Montreuil

    Rang-du-Fliers, France

  • Ch Bethune

    Béthune, France

  • Ch Boulogne-Sur-Mer

    Boulogne-sur-Mer, 62321, France

  • Ch Cambrai

    Cambrai, France

  • Ch Denain

    Denain, France

  • Ch Dunkerque

    Dunkirk, France

  • Ch Region de St-Omer

    Saint-Omer, France

  • Ch Tourcoing

    Tourcoing, France

  • Ch de Valenciennes

    Valenciennes, France

  • Clinique Teissier

    Valenciennes, France

  • Groupe Hospitalier Seclin Carvin

    Seclin, France

  • Hopital Prive La Louviere

    Lille, 59000, France

  • Hopital Saint Vincent - Saint Antoine

    Lille, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.