Flaxseed extract studied for PMS relief in midlife women
NCT ID NCT07310485
First seen Jun 27, 2026 · Last updated Sep 04, 2026 · Updated 1 time
Summary
This study looks at whether a flaxseed supplement (a type of phytoestrogen) can change how certain genes work and ease premenstrual syndrome (PMS) in women aged 40-55 who are near menopause. About 70 healthy women in Jordan will take either the supplement or a placebo for 12 weeks. The goal is to learn more about how plant compounds might affect hormone-related symptoms and ovarian aging.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2025
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 55 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Jordanian women aged 40-55 years * Regular menstrual cycles during the 90 days preceding enrollment * Body mass index between 19.0 and 29.9 kg/m² * Apparently healthy Exclusion Criteria: * Pregnancy or lactation * Current use of hormone replacement therapy or hormonal contraceptives * Diagnosis of a chronic metabolic, cardiovascular, hepatic, renal, autoimmune, or malignant disease * History of gynecological disorders or gynecological surgery * Use of dietary supplements or adherence to a special diet during the 90 days preceding enrollment * Habitual consumption of flaxseed or use of phytoestrogen supplements * Active bowel disease or malabsorption syndrome
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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the university of Jordan
Amman, Amman Governorate, 11942, Jordan
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Other studies related to the condition(s) this trial covers.
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