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Neck exercises and nerve zaps tested as migraine relief

NCT ID NCT07657377

Symptom relief Sponsor: Ankara Yildirim Beyazıt University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Aug 28, 2026 · Updated 3 times

Summary

This study tests a physiotherapy program that combines neck muscle exercises with a gentle nerve stimulation technique (transcutaneous vagus nerve stimulation) in 50 adults with migraine. The goal is to see if this approach can reduce pain, improve daily function, and boost quality of life, sleep, and mood. Participants will be followed for several weeks to track changes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
physiotherapy program including transcutaneous vagus nerve stimulation and cervical muscle exercises
What this could lead to
If it works, this could offer a drug-free way to reduce migraine pain and improve daily function and quality of life.
What could go wrong
This is a small, early-stage trial with only 50 participants, so results may not apply widely. The intervention may not provide significant benefit over standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Volunteering to participate in the study * Being between 18 and 55 years of age * Being diagnosed with migraine by a neurologist according to the International Classification of Headache Disorders 3 (ICHD-3) criteria Exclusion Criteria: * Diagnosis of other primary and/or secondary headaches in addition to migraine, * Coexisting neurological and/or rheumatological diseases, * Severe psychiatric disorders (bipolar disorder, schizophrenia, psychosis, etc.), * Pregnancy or lactation, * Malignancy, * Known arrhythmia or presence of any implanted electronic device, * Presence of sensory loss in the application area, * Having received physiotherapy or any other treatment in the head/neck region within the last 12 months, * History of head/neck trauma or surgery within the last 12 months.

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Conditions

The condition(s) this trial relates to.

migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Migraine

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Gazi Mustafa Kemal Occupational and Environmental Diseases Hospital

    RECRUITING

    Ankara, 06560, Turkey (Türkiye)

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