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Hand pain relief without surgery? physical therapy shows promise for carpal tunnel

NCT ID NCT04329247

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a specific physical therapy technique called median nerve neural mobilization can reduce pain in people with carpal tunnel syndrome. 74 participants were randomly assigned to receive the therapy or no treatment. The main goal was to measure pain reduction using a standard pain scale, and the researchers also looked at hand and arm function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
median nerve neural mobilization (a manual therapy maneuver)
What this could lead to
If it works, this could offer a non-surgical, drug-free option to ease pain and improve hand function for people with carpal tunnel syndrome.
What could go wrong
This is a small, completed trial with only 74 participants. The results may not apply to everyone, and the benefit over no treatment might be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

74 people

The number who actually took part.

Started

May 2020

Finished

Aug 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants must be medically diagnosed with unilateral carpal tunnel syndrome (with confirmative electrodiagnostic findings). * Full understanding of written and spoken Spanish (language). * Participants must freely consent to participate. * The presence of positive Phalen and Tinel signs. * The presence of carpal tunnel syndrome signs and symptoms Exclusion Criteria: * The lack to meet inclusion criterions, the presence of cognitive impairment. * Tumors * Cancer * Upper limb surgery or trauma * Pregnancy * Deformities of the (affected) upper limb * Recent skin injuries or infections (in the affected upper limb) * Autoimmune inflammatory conditions or flu type symptoms. * Allergy to gabapentin * Participants must not be (during the present investigation) under any type of pain reducing treatment (conservative, homeopathic, invasive or not invasive). * Metabolic neuropathy. * Obesity (body mass index over 30). * Participants who are not employed.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ciudad Hospitalaria Enrique Tejera

    Valencia, Carabobo, 2001, Venezuela

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